ReceptorBase, Inc. is a life sciences computational research and discovery company focused on the biology of complex receptor targets and signaling networks. ReceptorBase, Inc. is well positioned to provide leading-edge pharmaceutical drug target information for G-protein–coupled receptors (GPCRs) and several other gene families and offers a novel computational process to determine structures appropriate for the design of targeted chemical libraries that expedite the drug development process.

The completion of the sequence of the human genome has altered the approaches used in drug discovery. The evaluation of gene and protein sequences along with pharmacological data creates an opportunity to develop drugs for specific receptor targets in a directed fashion. Receptra Discovery is a process that interrelates the evolution of receptor proteins and known chemical specificity and selectivity as a starting point for constructive combinatorial chemistry. Our flexible ChemEvolve and ReceptorCS technologies allow us to tailor solutions to the specific needs and proprietary information of our clients. Chemistry designed and produced using ChemEvolve can be screened using existing technologies to select lead compounds. Receptra Discovery is computationally driven, quickly generating high-probability combinatorial libraries.